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Skill: Utilization of molecular visualization software to analyse the association between protein and DNA within a nucleosome. 

http://www.youtube.com/watch?v=vbueAuw96zA

Do on your own:

ühttp://www.rcsb.org/pdb/101/motm.do?momID=7

http://www.rcsb.org/pdb/explore/jmol.do?structureId=1AOI&bionumber=1

1.Identify the two copies of each histone protein by locating their “tails.”

2.Visualize the positively charged amino acids on the nucleosome core.  How do these help to form the nucleosome (with the negatively charged DNA)?